ROZEL 60MG-My Apple Pharma

                           Anti Cancer Drug-Rozel 60mg

Rozel 60mg:

rozel 60mg

PRODUCT DETAILS:

Brand Name : Rozel 

Composition : Denosumab 

Strength availability : 60mg 

Manufactured by : Intas pharmaceuticals 

Form : injection 

Pack : I injection in a prefilled syringe

Description:

Rozel 60mg belongs to novel, fully human IgG2 monoclonal antibody especially to receptor activator of nuclear factor kappa-B ligand (RANKL), restrain bone resorption markers in patients with a difference of metastatic tumors and is being examined in multiple clinical trials for the inhibition and treatment of bone metastases. Chemically, it exists of 2 heavy and 2 light chains. Each light chain contains of 215 amino acids. Each heavy chain contains of 448 amino acids with 4 intramolecular disulfides.

PRESCRIBED FOR:

 Rozel 60mg Treatment for patients having postmenopausal women with osteoporosis at high risk for fracture.
Treatment for patients with increase bone mass in men at more risk for fracture getting androgen deprivation therapy for non-metastatic prostate cancer.
Treatment for patients having to increase bone mass in women at more risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer.

DOSAGE

For adult :

Osteoporosis :

Rozel 60mg SC (subcutaneously) once every 6 months
Injection of drug should be done in upper arm, upper thigh or abdomen

Giant Cell Tumor of bone :

120mg SC, every 4 weeks with additional 120mg doses on days 8 and 15 of the 1st month treatment
Injection of drug should be done in upper arm, upper thigh or abdomen

Osteolytic Bone Metastases of Solid Tumors :

120mg subcutaneously every 4 weeks
Injection of drug should be done in upper arm, upper thigh or abdomen

Hypercalcemia :

120mg subcutaneously every 4 weeks
Injection of drug should be done in upper arm, upper thigh or abdomen

Dosage and administration in pediatric :

13 years and older and 45kg or more

Giant Cell Tumor of bone:

Dose of 120mg Rozel tablet given SC, every 4 weeks with additional 120mg doses on days 8 and 15 of the 1st month treatment

PRECAUTION:

• Before to start treatment with Rozel 60mg, discuss with the doctor about any other regimens you are using (including over-the-counter drugs, vitamins, or herbal remedies). Avoid having aspirin or products containing aspirin unless your doctor permits this.
• Rozel 60mg injection may improve the negative effects of immuno-suppressants. Especially the risk for serious infections may be increased. Inform your doctor of any immuno-suppressive drugs you early consume.
• Not to receive any type of vaccination without your doctor's consultation while admonishing denosumab.
• Use in pregnancy only if benefit to mother outweighs risk to fetus. Consult with doctor before the treatment
• During Rozel 60mg treatment do not breastfeed your infants.

DRUG INTERACTION:

No formal drug-drug interaction with denosumab during trials.
When interacting with some anticancer drug, orthopedic drugs, vaccines will lead to risk of adverse effects can be increased

CONTRAINDICATION:

Rozel 60mg is contraindicated in patients having Hypocalcemia, Pregnancy, Hypersensitivity

LACTATION:

Rozel 60mg is excreted into human milk is not known. Since possible for severe side effects occurs in nursing infants from Rozel 60mg injection, a decision should be considered that to discontinue nursing or discontinue the drug by giving preference of the importance of the drug to the mother.

STORAGE:

Store at 2℃ to 8℃ in the original container, avoid freeze
Before to administration keep at room temperature
Rozel 60mg protect from direct light and heat.

SIDE EFFECTS:

Common side effects :

 Fatigue, Muscle weakness, Phosphorus level reduced in blood, Nausea

Less common side effects :

Dyspnea, Hypocalcemia, Cough, Arthralgia, Limb pain, Eczema, Headache

Contact Details:

Phone :+91-9987711567

Email :applepharmaceutical@gmail.com

Email :info@myapplepharma.com